American chemist Alexander Shulgin personally tested hundreds of drugs, meticulously recording their effects in his lab notebooks. He is also credited with introducing MDMA to psychologists in the late 1970s.

Alexander Shulgin

This article is about the scientist. For the musician, see Alexander Shulgin (musician).

Alexander Theodore Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing MDMA (“ecstasy”, “mandy” or “molly”) to psychologists in the late 1970s for psychopharmaceutical use and for the discovery, synthesis and personal bioassay of over 230 psychoactive compounds for their psychedelic and entactogenic potential.

In 1991 and 1997, he and his wife Ann Shulgin compiled the books PIHKAL and TIHKAL (standing for Phenethylamines and Tryptamines I Have Known And Loved), from notebooks which extensively described their work … Continue Reading (7 minute read)

5 thoughts on “American chemist Alexander Shulgin personally tested hundreds of drugs, meticulously recording their effects in his lab notebooks. He is also credited with introducing MDMA to psychologists in the late 1970s.”

  1. CecondPercon

    His books TIHKAL and PIHKAL are both good reads for the first half, which is semi autobiographical and details his explorations and life. The the major portion of the book is a chemists guide to making the hundred of different chemicals he made along with mini trip reports. I believe the books are banned in some countries due to the detailed drug manufacturing instructions in the back. Although you would have to be a chemist to actually utilize the instructions. I believe he has a recipe for 5-MEO-DMT in there.

  2. amplifizzle

    He got in some trouble once because his lab was kinda sloppy but he was cranking this shit out with the blessing of the DEA and a full schedule 1 license to produce any drug.

  3. gozigzagman

    Tried 2c-e twice, here’s what is written in his book PiHKAL about it:

    “Here is another of the magical half-dozen. The range is purposefully broad. At 10 milligrams there have been some pretty rich +++[nb 1] experiences, and yet I have had the report from one young lady of a 30 milligram trial that was very frightening. My first experience with 2C-E was really profound, and it is the substance of a chapter within the story. Several people have said, about 2C-E, “I don’t think I like it, since it isn’t that much fun. But I intend to explore it again.” There is something here that will reward the experimenter. Someday, the full character of 2C-E will be understood, but for the moment, let it rest as being a difficult and worth-while material. A very much worth-while material.”

    Can confirm…2c-e was really weird.

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